Increased methacholine sensitivity after eucapnic voluntary hyperpnea

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Increased methacholine sensitivity after eucapnic voluntary hyperpnea

Findings In athletes with AHR, the PC20 (expressed as the mean of double concentrations (DC) ± standard error) was 0.7 ± 1.2 DC lower when MIT followed EVH (p = 0.015), while there was no significant difference in athletes without AHR (-0.4 ± 0.8 DC) nor in control subjects (0.4 ± 0.7 DC). When grouping subjects based on the EVH response, those with a positive response (FEV1 fall ≥ 10%) had a m...

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Airway Response to Methacholine following Eucapnic Voluntary Hyperpnea in Athletes

AIM To evaluate the changes in airway responsiveness to methacholine inhalation test (MIT) when performed after an eucapnic voluntary hyperpnea challenge (EVH) in athletes. METHODS Two MIT preceded (visit 1) or not (visit 2) by an EVH, were performed in 28 athletes and 24 non-athletes. Twelve athletes and 13 non-athletes had airway hyperresponsiveness (AHR) to methacholine, and 11 athletes an...

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Exhaled breath temperature in asthmatics and controls after eucapnic voluntary hyperventilation and a methacholine challenge test.

BACKGROUND It has been suggested that exhaled breath temperature (EBT) is increased in asthmatic subjects. OBJECTIVES Our aim was to investigate EBT in asthmatics compared to healthy controls before and after eucapnic voluntary hyperventilation (EVH) and a methacholine challenge test (MCT). METHODS A total of 26 asthmatics and 29 healthy controls were included. Forced expiratory volume in 1...

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Is Performance of a Modified Eucapnic Voluntary Hyperpnea Test in High Ventilation Athletes Reproducible?

PURPOSE Exercise-induced bronchoconstriction (EIB) is common in "high ventilation" athletes, and the Eucapnic Voluntary Hyperpnea (EVH) airway provocation test is the standard EIB screen. Although the EVH test is widely used, the in-test performance in high ventilation athletes as well as the reproducibility of that performance has not been determined. Reproducibility of pre- and post-test spir...

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Eucapnic Voluntary Hyperpnea: Gold Standard for Diagnosing Exercise-Induced Bronchoconstriction in Athletes?

In athletes, a secure diagnos is of exercise-induced bronchoconstriction (EIB) is dependent on objective testing. Evaluating spirometric indices of airflow before and following an exercise bout is intuitively the optimal means for the diagnosis; however, this approach is recognized as having several key limitations. Accordingly, alternative indirect bronchoprovocation tests have been recommende...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2010

ISSN: 1710-1492

DOI: 10.1186/1710-1492-6-s3-p12